Article
Phenotypic, genetic, and genome-wide structure in the metabolic syndrome.
BMC genetics - 31 Dec 2003
Martin Lisa J, North Kari E, Dyer Tom, Blangero John, Comuzzie Anthony G, Williams Jeff
Abstract excerpt
BACKGROUND: Insulin resistance, obesity, dyslipidemia, and high blood pressure characterize the metabolic syndrome. In an effort to explore the utility of different multivariate methods of data reduction to better understand the genetic influences on the aggregation of metabolic syndrome phenotypes, we calculated phenotypic, genetic, and genome-wide LOD score correlation matrices using five traits (total...
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