Article
Matrigel supports neural, melanocytic and chondrogenic differentiation of trunk neural crest cells.
The International journal of developmental biology - 1 Jan 2013
Ramos-Hryb Ana B, Da-Costa Meline C, Trentin Andréa G, Calloni Giordano W
Abstract excerpt
The neural crest (NC) is composed of highly multipotent precursor cells able to differentiate into both neural and mesenchymal phenotypes. Until now, most studies focusing on NC cell differentiation have been performed with traditional two-dimensional (2D) cell culture systems. However, such culture systems do not reflect the complex three-dimensional (3D) microenvironments of in vivo NC cells. To address this...
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