Article
Epidermal growth factor (EGF) promotes the in vitro differentiation of neural crest cells to neurons and melanocytes.
Cellular and molecular neurobiology - 1 Dec 2009
Garcez Ricardo Castilho, Teixeira Bianca Luise, Schmitt Suelen dos Santos, Alvarez-Silva Márcio, Trentin Andréa Gonçalves
Abstract excerpt
Proliferation of neural crest (NC) stem cells and their subsequent differentiation into different neural cell types are key early events in the development of the peripheral nervous system. Soluble growth factors present at the sites where NC cells migrate are critical to the development of NC derivatives in each part of the body. In the present study, we further investigate the effect of microenvironmental...
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