Article
Role of co-inherited Gilbert syndrome on hyperbilirubinemia in Indian beta thalassemia patients.
Hematology (Amsterdam, Netherlands) - 1 Oct 2014
Dabke Pooja S, Colah Roshan B, Ghosh Kanjaksha K, Nadkarni Anita H
Abstract excerpt
BACKGROUND: Gilbert syndrome is characterized by mild unconjugated hyperbilirubinemia. The high levels of bilirubin could be related to the co-inheritance of Gilbert syndrome determined either by mutations of the coding region or by variation in the (TA)n motifs of the promoter region of the bilirubin UGT1A1 gene. The co-inheritance of Gilbert syndrome has been reported to elevate bilirubin levels in beta...
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