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Article

Role of co-inherited Gilbert syndrome on hyperbilirubinemia in Indian beta thalassemia patients.

Hematology (Amsterdam, Netherlands) - 1 Oct 2014

Dabke Pooja S, Colah Roshan B, Ghosh Kanjaksha K, Nadkarni Anita H

Abstract excerpt

BACKGROUND: Gilbert syndrome is characterized by mild unconjugated hyperbilirubinemia. The high levels of bilirubin could be related to the co-inheritance of Gilbert syndrome determined either by mutations of the coding region or by variation in the (TA)n motifs of the promoter region of the bilirubin UGT1A1 gene. The co-inheritance of Gilbert syndrome has been reported to elevate bilirubin levels in beta...

Topics

Bilirubin
Dinucleotide Repeats
Gene Frequency
Genotype
Gilbert Disease
Glucuronosyltransferase
Humans
Hyperbilirubinemia
India
Mutation
Nucleotide Motifs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

beta-Thalassemia

Source

Identifiers

PMID: 24620945
DOI: 10.1179/1607845413Y.0000000142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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