Hyperbilirubinaemia in heterozygous beta-thalassaemia is related to co-inherited Gilbert's syndrome.

doi:10.1046/j.1365-2141.1997.3703182.x

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Article

Hyperbilirubinaemia in heterozygous beta-thalassaemia is related to co-inherited Gilbert's syndrome.

British journal of haematology - 1 Nov 1997

Galanello R, Perseu L, Melis M A, Cipollina L, Barella S, Giagu N, Turco M P, Maccioni O, Cao A

Abstract excerpt

The reasons why heterozygotes for beta-thalassaemia have considerable variation in serum bilirubin levels are unknown. High levels of bilirubin could be related to the co-inherited Gilbert's syndrome, determined either by mutations of the coding region or by variation in the A(TA)nTAA motif of th...

Topics

Genotype
Gilbert Disease
Globins
Heterozygote
Humans
Hyperbilirubinemia
Mutation
beta-Thalassemia

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