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Article

ERβ regulates NSCLC phenotypes by controlling oncogenic RAS signaling.

Molecular cancer research : MCR - 1 Jun 2014

Nikolos Fotis, Thomas Christoforos, Rajapaksa Gayani, Bado Igor, Gustafsson Jan-Åke

Abstract excerpt

UNLABELLED: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. In addition to the aberrant growth factor signaling, dysregulation of other pathways, such as those mediated by estrogens and their receptors, has been linked to NSCLC initiation and progression. Although the expression of wild-type estrogen receptor β (ERβ1) has been associated with prolonged disease-free...

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Source

Identifiers

PMID: 24618619
DOI: 10.1158/1541-7786.MCR-13-0663

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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