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Article

Expression of estrogen receptor beta predicts a clinical response and longer progression-free survival after treatment with EGFR-TKI for adenocarcinoma of the lung.

Lung cancer (Amsterdam, Netherlands) - 1 Mar 2011

Nose Naohiro, Uramoto Hidetaka, Iwata Teruo, Hanagiri Takeshi, Yasumoto Kosei

Abstract excerpt

PURPOSE: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (EGFR-TKI) demonstrates a dramatic clinical response for the lung adenocarcinoma patients harboring a somatic mutation of EGFR. Such EGFR mutations are frequently found in adenocarcinoma with a strong expression of estrogen receptor (ER) beta, which has been shown to correlate with a favorable prognosis for the patients with EGFR...

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Identifiers

PMID: 20615575
DOI: 10.1016/j.lungcan.2010.06.009

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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