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Article

The Association Between Global DNA Methylation and Telomere Length in a Longitudinal Study of Boilermakers

24 Feb 2014

Abstract excerpt

The objectives of this study were to determine if global DNA methylation, as reflected in LINE-1 and Alu elements, is associated with telomere length and whether it modifies the rate of telomeric change. A repeated-measures longitudinal study was performed with a panel of 87 boilermaker subjects. The follow-up period was 29 months. LINE-1 and Alu methylation was determined using pyrosequencing. Leukocyte relative...

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PMID: 24616077
DOI: 10.1002/gepi.21796

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