Article
Adult global DNA methylation in relation to pre-natal nutrition
29 Sept 2011
Abstract excerpt
BACKGROUND: Exposure to a pre-natal famine environment has been associated with a persistent decrease in DNA methylation of the IGF2 gene, although study findings on other loci have been highly variable. There have been no studies to date of the relation between pre-natal famine and overall global DNA methylation in adulthood. METHODS: Our study population includes 350 births with pre-natal exposure to the Dutch...
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