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Article

Differential requirement for PBP1a and PBP1b in in vivo and in vitro fitness of Vibrio cholerae.

Infection and immunity - 1 May 2014

Dörr Tobias, Möll Andrea, Chao Michael C, Cava Felipe, Lam Hubert, Davis Brigid M, Waldor Matthew K

Abstract excerpt

We investigated the roles of the Vibrio cholerae high-molecular-weight bifunctional penicillin binding proteins, PBP1a and PBP1b, in the fitness of this enteric pathogen. Using a screen for synthetic lethality, we found that the V. cholerae PBP1a and PBP1b proteins, like their Escherichia coli ho...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24614657
DOI: 10.1128/IAI.00012-14
PMCID: PMC3993429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24614657-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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