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Mitochondrial biogenesis in neurodegeneration

16 Mar 2017

Abstract excerpt

Mitochondria play a key role in energy production, calcium homeostasis, cell survival, and death. Adverse stimulations including neurodegenerative diseases may result in mitochondrial dynamic imbalance, free radical production, calcium accumulation, intrinsic cell death pathway activation and eventually cell death. Therefore, preserving or promoting mitochondrial function is a potential therapeutic target for the...

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PMID: 28301064
DOI: 10.1002/jnr.24042

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