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Mitochondrial dysfunction and its association with age-related disorders

2 Jul 2024

Abstract excerpt

Aging is a complex process that features a functional decline in many organelles. Various factors influence the aging process, such as chromosomal abnormalities, epigenetic changes, telomere shortening, oxidative stress, and mitochondrial dysfunction. Mitochondrial dysfunction significantly impacts aging because mitochondria regulate cellular energy, oxidative balance, and calcium levels. Mitochondrial integrity...

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PMID: 39015222
DOI: 10.3389/fphys.2024.1384966

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