Article
Promoter polymorphisms of ST3GAL4 and ST6GAL1 genes and associations with risk of premalignant and malignant lesions of the cervix.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Rivera-Juarez Maria de Los Angeles, Rosas-Murrieta Nora Hilda, Mendieta-Carmona Victoriano, Hernandez-Pacheco Raquel Esneidy, Zamora-Ginez Irma, Rodea-Avila Carlos, Apresa-Garcia Teresa, Garay-Villar Onix, Aguilar-Lemarroy Adriana, Jave-Suarez Luis Felipe, Diaz-Orea Maria Alicia, Milflores-Flores Lorena, Reyes-Salinas Juan Salvador, Ceja-Utrera Francisco Javier, Vazquez-Zamora Victor Javier, Vargas-Maldonado Tomas, Reyes-Carmona Sandra, Sosa-Jurado Francisca, Santos-Lopez Gerardo, Reyes-Leyva Julio, Vallejo-Ruiz Veronica
Abstract excerpt
Sialyltransferase gene expression is altered in several cancers, including examples in the cervix. Transcriptional regulation of the responsible genes depends on different promoters. We aimed to determine the association of single-nucleotide polymorphisms in the B3 promoter of the ST3GAL4 gene and the P1 promoter of the ST6GAL1 gene with cervical premalignant lesions or cervical cancer. A blood sample and/or...
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