Article
HLA polymorphism and susceptibility to end-stage renal disease in Cantonese patients awaiting kidney transplantation.
PloS one - 1 Jan 2014
Cao Qiong, Xie Di, Liu Jiangmei, Zou Hongyan, Zhang Yinze, Zhang Hong, Zhang Zhimei, Xue Hao, Zhou Jiyuan, Chen Pingyan
Abstract excerpt
BACKGROUND: End-Stage Renal Disease (ESRD) is a worldwide public health problem. Currently, many genome-wide association studies have suggested a potential association between human leukocyte antigen (HLA) and ESRD by uncovering a causal relationship between HLA and glomerulonephritis. However, previous studies, which investigated the HLA polymorphism and its association with ESRD, were performed with the modest...
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