Article
Revisiting the association between human leukocyte antigen and end-stage renal disease.
PloS one - 1 Jan 2020
Noureen Naila, Shah Farhad Ali, Lisec Jan, Usman Hina, Khalid Mohammad, Munir Rimsha, Zaidi Nousheen
Abstract excerpt
Multiple works have studied possible associations between human leukocyte antigen (HLA) alleles and end stage renal disease (ESRD) showing, however, contradictory and inconsistent results. Here, we revisit the association between ESRD and HLA antigens, comparing HLA polymorphism (at HLA-A, -B, -C, -DRB1, -DQB1 and DQA1 loci) in ESRD patients (n = 497) and controls (n = 672). Our data identified several HLA...
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