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Association between the polymorphism of HLA and ESRD in Dalian Han population located in north of China.

Immunological investigations - 1 Feb 2018

Shao Lin-Nan, Yang Yang, Zhang Shu-Ting, Zhou Shi-Hang, Duan Ying, Meng Qing-Li, Liang Xiao-Hua, Yu Wei-Jian

Abstract excerpt

BACKGROUND: End-stage renal disease (ESRD), the last stage of chronic renal failure, is a global health problem. The number of ESRD patients worldwide is increasing faster than the number of kidneys available per year for renal transplantation. Most of the ESRD patients are awaiting renal transplantation. The immune response to the transplanted kidney is directed mainly against mismatched human leukocyte antigen...

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PMID: 29257902
DOI: 10.1080/08820139.2017.1416397

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