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Article

Identification of Genetic Variations in HLA Region for Kidney Functions.

HLA - 1 Jun 2025

Chou Wan-Hsuan, Wei Chun-Yu, Lin Min-Rou, Chang Che-Mai, Gruber Stephen B, Wu Mai-Szu, Chang Wei-Chiao

Abstract excerpt

HLA allelic polymorphisms are associated with a variety of kidney-related traits in different populations. Although Taiwanese-specific genetic variants associated with kidney function have been reported, the role of HLA alleles is unclear. In this study, the association between eGFR and genetic variations in the HLA region was explored in a cohort of 59,448 Taiwanese subjects. A total of 448 genetic variations in...

Read the complete abstract on PubMed

Topics

Adult
Female
Humans
Male
Middle Aged
Alleles
Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Glomerular Filtration Rate

HLA-C Antigens

HLA-DQ alpha-Chains

HLA-DQ beta-Chains

HLA-DRB1 Chains

Kidney

Polymorphism, Single Nucleotide

Taiwan

East Asian People

Source

Identifiers

PMID: 40551377
DOI: 10.1111/tan.70284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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