Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental and behavioral effects of toe clipping on neonatal and preweanling mice with and without vapocoolant anesthesia.

Journal of the American Association for Laboratory Animal Science : JAALAS - 1 Mar 2014

Paluch Lee-Ronn, Lieggi Christine C, Dumont Magali, Monette Sebastien, Riedel Elyn R, Lipman Neil S

Abstract excerpt

Toe clipping is used to identify and genotype preweanling mice, but the procedure generates concerns relevant to pain and distress. The few pertinent studies available evaluated mice between postnatal days (PND) 3 and 7, advocate the use of toe clipping in mice PND 7 or younger, and identify handling as the most distressing aspect of the procedure. Because both toe and tail clipping may be necessary in older mice...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia
Share to Animal Husbandry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Animals, Laboratory

Share to Animals, Newborn

Share to Behavior, Animal

Share to Random Allocation

Source

Open in PubMed Open full text

Identifiers

PMID: 24602538
PMCID: PMC3966268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental and behavioral effects of toe clipping on neonatal and preweanling mice with and without vapocoolant anesthesia.PMID 24602538Read ↗

Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains.Semantic proximity Read ↗

Pinna Edge Biopsy of 7 and 21 Day Old C57BL/6 Mice as a Method for Identification and Genotyping.Semantic proximity Read ↗

Preweanling sensorial and motor development in laboratory mice: quantitative trait loci mapping.Semantic proximity Read ↗

The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli.Semantic proximity Read ↗

Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide.Semantic proximity Read ↗

Sensory neuron development in mouse coccygeal vertebrae and its relationship to tail biopsies for genotyping.Semantic proximity Read ↗

Local cryoanalgesia is effective for tail-tip biopsy in mice.Semantic proximity Read ↗

Epidermal Hyperproliferation and Decreased Skin Barrier Function in Mice Overexpressing Stratum Corneum Chymotryptic EnzymeSemantic proximity Read ↗

Measuring pain in the (knockout) mouse: big challenges in a small mammal.Semantic proximity Read ↗

Routine tail suspension husbandry facilitates onset of seizure susceptibility in EL mice.Semantic proximity Read ↗

Patterned acquisition of skin barrier function during developmentSemantic proximity Read ↗

[Interstrain differences in the maturation of congenital reflexes in 101/HY and CBA mice in early postnatal ontogeny].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.