Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Measuring pain in the (knockout) mouse: big challenges in a small mammal.

Behavioural brain research - 1 Nov 2001

Wilson S G, Mogil J S

Abstract excerpt

The increasing popularity of the mouse as a subject in basic science studies of pain can largely be attributed to the development of transgenic "knockout" technology in this species only. To take advantage of this biological technique, many investigators are rushing to adapt to the mouse experimental protocols that were designed for the rat. However, the myriad physiological and behavioral differences between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Mice, Knockout
Share to Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pain Measurement

Share to Pain Threshold

Share to Reference Standards

Share to Species Specificity

Source

Identifiers

PMID: 11682095
DOI: 10.1016/s0166-4328(01)00281-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Measuring pain in the (knockout) mouse: big challenges in a small mammal.PMID 11682095Read ↗

Psychophysics of a Nociceptive Test in the Mouse: Ambient Temperature as a Key Factor for VariationSemantic proximity Read ↗

Analgesic treatment with buprenorphine should be adapted to the mouse strain.Semantic proximity Read ↗

The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli.Semantic proximity Read ↗

Hot and Cold Nociception Are Genetically CorrelatedSemantic proximity Read ↗

Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay.Semantic proximity Read ↗

Clinical relevance of chronic neuropathic pain phenotypes in mice: A comprehensive behavioral analysis.Semantic proximity Read ↗

Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception.Semantic proximity Read ↗

Pain genes?: natural variation and transgenic mutants.Semantic proximity Read ↗

Transgenic studies of pain and analgesia: mutation or background genotype?Semantic proximity Read ↗

A high-throughput machine vision-based univariate scale for pain and analgesia in miceSemantic proximity Read ↗

Influence of nociception and stress-induced antinociception on genetic variation in isoflurane anesthetic potency among mouse strains.Semantic proximity Read ↗

Dose-dependent, opioid-induced sleep disruption is partially mediated by motor activity but not by body temperature in C57BL/6J miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.