Article
Genetically determined transient edema found in the WB/ReJ mouse strain in a teratogenic survey with acetazolamide.
Teratology - 1 Dec 1990
Biddle F G
Abstract excerpt
A continuing survey of the genetic variability of different mouse strains to acetazolamide teratogenesis demonstrated the WB/ReJ strain expresses a high frequency of induced subcutaneous edema in day 15 fetuses. In treated WB/ReJ fetuses, the probability of expression of edema is independent of the expression of forelimb ectrodactyly and, with the dosage regime, there is no significant increase in...
Topics
- Acetazolamide
- Animals
- Crosses, Genetic
- Edema
- Female
- Fetal Diseases
- Genetic Predisposition to Disease
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mice, Mutant Strains
