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Article

The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli.

PloS one - 30 Jul 2009

Morales Maria Elena P, Gereau Robert W

Abstract excerpt

Removal of a small segment of tail at weaning is a common method used to obtain tissue for the isolation of genomic DNA to identify genetically modified mice. When genetically manipulated mice are used for pain research, this practice could result in confounding changes to the animals' responses to noxious stimuli. In this study, we sought to systematically investigate whether tail biopsy representative of that...

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PMID: 19649248
DOI: 10.1371/journal.pone.0006457
PMCID: PMC2714470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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