Article
Synergy between mannose-binding lectin gene polymorphisms and supplementation with vitamin A influences susceptibility to HIV infection in infants born to HIV-positive mothers.
The American journal of clinical nutrition - 1 Sept 2006
Kuhn Louise, Coutsoudis Anna, Trabattoni Daria, Archary Derseree, Rossi Tatiana, Segat Ludovica, Clerici Mario, Crovella Sergio
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL-2) allele variants are associated with deficiencies in innate immunity and have been found to be correlated with HIV infection in adults and children. OBJECTIVE: We tested whether MBL-2 variants among infants born to HIV-positive mothers have an increased susceptibility to HIV. DESIGN: MBL-2 allele variants were measured among 225 infants born to HIV-positive mothers...
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