Article
ESR1 gene polymorphisms PvuII (rs2234693T>C) and XbaI (rs9340799A>G) may not be directly correlated with cardiovascular disease risk.
Genetics and molecular research : GMR - 30 Oct 2015
Jiang N, Yang G, Peng C L
Abstract excerpt
The aim of this meta-analysis was to evaluate the correlations between the estrogen receptor 1 (ESR1) gene polymorphisms PvuII (rs2234693T>C) and XbaI (rs9340799A>G) and the risk of cardiovascular disease (CVD). Case-control studies were screened and selected from a larger group of studies that were retrieved through a comprehensive search of scientific literature databases, which was complemented by manual...
Topics
- Alleles
- Cardiovascular Diseases
- Case-Control Studies
- Estrogen Receptor alpha
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Linkage Disequilibrium
- Odds Ratio
- Polymorphism, Restriction Fragment Length
