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Article

The physiological and pathophysiological functions of renal and extrarenal vasopressin V2 receptors.

American journal of physiology. Renal physiology - 1 May 2014

Juul Kristian Vinter, Bichet Daniel G, Nielsen Søren, Nørgaard Jens Peter

Abstract excerpt

The arginine vasopressin (AVP) type 2 receptor (V2R) is unique among AVP receptor subtypes in signaling through cAMP. Its key function is in the kidneys, facilitating the urine concentrating mechanism through the AVP/V2 type receptor/aquaporin 2 system in the medullary and cortical collecting ducts. Recent clinical and research observations strongly support the existence of an extrarenal V2R. The clinical...

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Source

Identifiers

PMID: 24598801
DOI: 10.1152/ajprenal.00604.2013

Genes

AVP
AVPR2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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