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Article

A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro.

Journal of biomolecular screening - 1 Jul 2014

Allali-Hassani Abdellah, Kuznetsova Ekaterina, Hajian Taraneh, Wu Hong, Dombrovski Ludmila, Li Yanjun, Gräslund Susanne, Arrowsmith Cheryl H, Schapira Matthieu, Vedadi Masoud

Abstract excerpt

The nuclear receptor SET domain-containing family of proteins (NSD1, NSD2, and NSD3) is known to mono- and dimethylate lysine 36 of histone H3 (H3K36). Overexpression and translocation of NSDs have been widely implicated in a variety of diseases including cancers. Although the substrate specificity of NSDs has been a subject of many valuable studies, the activity of these proteins has never been fully...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24595546
DOI: 10.1177/1087057114525854

Genes

NSD2
SET
NSD1
NSD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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