Article
The type 2 secretion Pseudopilin, gspJ, is required for multihost pathogenicity of Burkholderia cenocepacia AU1054.
Infection and immunity - 1 Oct 2010
Somvanshi Vishal S, Viswanathan Poorna, Jacobs Janette L, Mulks Martha H, Sundin George W, Ciche Todd A
Abstract excerpt
Burkholderia cenocepacia AU1054 is an opportunistic pathogen isolated from the blood of a person with cystic fibrosis. AU1054 is a multihost pathogen causing rapid pathogenicity to Caenorhabditis elegans nematodes. Within 24 h, AU1054 causes greater than 50% mortality, reduced growth, emaciated body, distended intestinal lumen, rectal swelling, and prolific infection of the nematode intestine. To determine...
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