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Article

GRK5 intronic (CA)n polymorphisms associated with type 2 diabetes in Chinese Hainan Island.

PloS one - 1 Jan 2014

Xia Zhenfang, Yang Tubao, Wang Zhuansuo, Dong Jianping, Liang Chunyan

Abstract excerpt

A genome-wide association study had showed G-protein-coupled receptor kinase 5 (GRK5) rs10886471 was related to the risk of type 2 diabetes mellitus (T2DM) through upregulated GRK5 mRNA expression. Rs10886471 is located in the intron region of GRK5. However, the mechanism by which intronic SNP affects gene expression remains unclear, whether the effect on gene expression depends on the intronic short tandem...

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Identifiers

PMID: 24594703
DOI: 10.1371/journal.pone.0090597
PMCID: PMC3940906

Genes

GRK5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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