Article
Polymorphisms in Four Genes (KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963) and Their Correlation with Type 2 Diabetes Mellitus in Han Chinese in Henan Province, China.
International journal of environmental research and public health - 26 Feb 2016
Gao Kaiping, Wang Jinjin, Li Linlin, Zhai Yujia, Ren Yongcheng, You Haifei, Wang Bingyuan, Wu Xuli, Li Jianna, Liu Zichen, Li Xiong, Huang Yaxin, Luo Xin-Ping, Hu Dongsheng, Ohno Kinji, Wang Chongjian
Abstract excerpt
Genetic variants at KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963 have been associated with type 2 diabetes mellitus (T2DM), but the results are contradictory in Chinese populations. The aim of the present study was to investigate the association of these four SNPs with T2DM in a large population of Han Chinese at Henan province, China. Seven-hundred-thirty-six patients with T2DM (cases) and...