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Article

Genetic determinants of chronic obstructive pulmonary disease in South Indian male smokers.

PloS one - 1 Jan 2014

Arja Cholendra, Ravuri Rajasekhara Reddy, Pulamaghatta Venugopal N, Surapaneni Krishna Mohan, Raya Premanand, Adimoolam Chandrasekhar, Kanala Kodanda Reddy

Abstract excerpt

The development of chronic obstructive pulmonary disease, upon exposure to tobacco smoke, is the cumulative effect of defects in several genes. With the aim of understanding the genetic structure that is characteristic of our patient population, we selected forty two single nucleotide polymorphisms of twenty genes based on previous studies and genotyped a total of 382 samples, which included 236 patients and 146...

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Identifiers

PMID: 24587150
DOI: 10.1371/journal.pone.0089957
PMCID: PMC3933698

Genes

MMP12
SERPINE2
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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