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Article

Realistic three dimensional fitness landscapes generated by self organizing maps for the analysis of experimental HIV-1 evolution.

PloS one - 1 Jan 2014

Lorenzo-Redondo Ramón, Delgado Soledad, Morán Federico, Lopez-Galindez Cecilio

Abstract excerpt

Human Immunodeficiency Virus type 1 (HIV-1) because of high mutation rates, large population sizes, and rapid replication, exhibits complex evolutionary strategies. For the analysis of evolutionary processes, the graphical representation of fitness landscapes provides a significant advantage. The experimental determination of viral fitness remains, in general, difficult and consequently most published fitness...

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Identifiers

PMID: 24586344
DOI: 10.1371/journal.pone.0088579
PMCID: PMC3938428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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