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Sperm Protamine mRNA Ratio and DNA Fragmentation Index Represent Reliable Clinical Biomarkers for Men with Varicocele after Microsurgical Varicocele Ligation

25 Feb 2014

Abstract excerpt

PURPOSE: We investigated whether the sperm protamine-1/2 mRNA ratio and DNA fragmentation index are reliable biomarkers in patients with clinical varicocele. MATERIALS AND METHODS: We performed a prospective study in 42 subfertile patients with left clinical varicocele and 10 normozoospermic healthy donors with proven fertility. All patients and female partners were seen 3 and 6 months after varicocelectomy for...

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PMID: 24582535
DOI: 10.1016/j.juro.2014.02.046

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