Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Integrity Is Compromised in Protamine‐Deficient Human Sperm

12 Nov 2005

Abstract excerpt

The objective of this study was to examine the relationship between DNA integrity and protamines in human sperm. One hundred forty-nine male infertility patients were included in an Institutional Review Board-approved study. Sperm were evaluated for DNA fragmentation using the DNA Integrity Assay, a test equivalent to the sperm chromatin structure assay (SCSA). Additionally, nuclear proteins were extracted and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Sperm and Testicular Function
Share to Reproductive Biology and Fertility
Share to Reproductive Health and Technologies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16291969
DOI: 10.2164/jandrol.05063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Integrity Is Compromised in Protamine‐Deficient Human SpermPMID 16291969Read ↗

Protamine Levels Vary Between Individual Sperm Cells of Infertile Human Males and Correlate With Viability and DNA IntegritySemantic proximity Read ↗

Aberrant protamine content in sperm and consequential implications for infertility treatment.Semantic proximity Read ↗

The Clinical Utility of the Protamine 1/Protamine 2 Ratio in SpermSemantic proximity Read ↗

Protamine 1 to protamine 2 ratio correlates with dynamic aspects of DNA fragmentation in human spermSemantic proximity Read ↗

Both protamine-1 to protamine-2 mRNA ratio and Bcl2 mRNA content in testicular spermatids and ejaculated spermatozoa discriminate between fertile and infertile menSemantic proximity Read ↗

Altered Protamine 2 Expression Is Uncommon In Donors of Known Fertility, but Common Among Men With Poor Fertilizing Capacity, and May Reflect Other Abnormalities of SpermiogenesisSemantic proximity Read ↗

Relationships between human sperm protamines, DNA damage and assisted reproduction outcomesSemantic proximity Read ↗

Sperm DNA damage: importance in the era of assisted reproductionSemantic proximity Read ↗

Protamines and DNA integrity as a biomarkers of sperm quality and assisted conception outcomeSemantic proximity Read ↗

Protamine/DNA Ratios and DNA Damage in Native and Density Gradient Centrifuged Sperm From Infertile PatientsSemantic proximity Read ↗

Protamine alterations in human spermatozoa.Semantic proximity Read ↗

The Role of Protamine 2 Gene Expression and Caspase 9 Activity in Male InfertilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.