Article
General assessment of copy number variation in normal and tumor tissues of the domestic dog (Canis lupus familiaris).
Journal of applied genetics - 1 Aug 2014
Gurgul Artur, Żukowski Kacper, Ślaska Brygida, Semik Ewelina, Pawlina Klaudia, Ząbek Tomasz, Jasielczuk Igor, Bugno-Poniewierska Monika
Abstract excerpt
In recent years, characterization of a copy number variation (CNV) of the genomic DNA has provided evidence for the relationship of this type of genetic variation with the occurrence of a broad spectrum of diseases, including cancer lesions. Copy number variants (CNVs) also occur in the genomes of healthy individuals as a result of abnormal recombination processes in germ cells and have a hereditary character...
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