Article
Efficient identification of context dependent subgroups of risk from genome-wide association studies.
Statistical applications in genetics and molecular biology - 1 Apr 2014
Dyson Greg, Sing Charles F
Abstract excerpt
We have developed a modified Patient Rule-Induction Method (PRIM) as an alternative strategy for analyzing representative samples of non-experimental human data to estimate and test the role of genomic variations as predictors of disease risk in etiologically heterogeneous sub-samples. A computational limit of the proposed strategy is encountered when the number of genomic variations (predictor variables) under...
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