Article
Cyclin D1 G870A polymorphism is associated with risk and clinicopathologic characteristics of bladder cancer.
DNA and cell biology - 1 Oct 2010
Yuan Lin, Gu Xiaojian, Shao Jianfeng, Wang Meilin, Wang Miaomiao, Zhu Qingyi, Zhang Zhengdong
Abstract excerpt
Cyclin D1 (CCND1) is a key protein in regulation of cell cycle at the G1-to-S transition phase and is essential for regulation of cell proliferation, differentiation, and transcriptional control. We hypothesized that the CCND1 G870A polymorphism is associated with risk of bladder cancer. The CCND1 G870A polymorphism was genotyped in a hospital-based case-control study of 402 bladder cancer cases and 402 control...
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