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Article

Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations.

Nature communications - 26 Feb 2014

Ramakrishna Suresh, Cho Seung Woo, Kim Sojung, Song Myungjae, Gopalappa Ramu, Kim Jin-Soo, Kim Hyongbum

Abstract excerpt

RNA-guided endonucleases (RGENs), which are based on the clustered, regularly interspaced, short palindromic repeat (CRISPR)-CRISPR-associated (Cas) system, have recently emerged as a simple and efficient tool for genome editing. However, the activities of prepared RGENs are sometimes low, hamper...

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PMID: 24569644
DOI: 10.1038/ncomms4378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24569644-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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