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Article

Surrogate reporters for enrichment of cells with nuclease-induced mutations.

Nature methods - 9 Oct 2011

Kim Hyojin, Um Eunji, Cho Sung-Rae, Jung Chorong, Kim Hyongbum, Kim Jin-Soo

Abstract excerpt

Zinc-finger nucleases (ZFNs) and TAL-effector nucleases (TALENs) are powerful tools for creating genetic modifications in eukaryotic cells and organisms. But wild-type and mutant cells that contain genetic modifications induced by these programmable nucleases are often phenotypically indistinguis...

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PMID: 21983922
DOI: 10.1038/nmeth.1733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21983922-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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