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Article

Antibody humanization methods – a review and update

2 Aug 2013

Abstract excerpt

This article reviews recent advances achieved during recent years on various aspects of antibody humanization theories and techniques. Common methods for producing humanized antibodies including framework-homology-based humanization, germline humanization, complementary determining regions (CDR)-homology-based humanization and specificity determining residues (SDR) grafting, as well as advantages and...

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PMID: 24568279
DOI: 10.1080/02648725.2013.801235

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