Article
On the origin of glioma.
Upsala journal of medical sciences - 1 May 2012
Jiang Yiwen, Uhrbom Lene
Abstract excerpt
Glioma is the most frequent primary brain tumor of adults that has a presumably glial origin. Although our knowledge regarding molecular mechanisms and signaling pathways involved in gliomagenesis has increased immensely during the past decade, high-grade glioma remains a lethal disease with dismal prognosis. The failure of current therapies has to a large extent been ascribed the functional heterogeneity of...
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