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KLF5 Is Activated by Gene Amplification in Gastric Cancer and Is Essential for Gastric Cell Proliferation.

Cells - 24 Apr 2021

Chen Wei, Zhang Jian, Fu Huafeng, Hou Xun, Su Qiao, He Yulong, Yang Dongjie

Abstract excerpt

Gastric cancer is the third leading cause of cancer death worldwide. In this study, we tried to clarify the function of KLF5 in gastric cancer. Copy number variation (CNV) and the expression of KLF5 were interrogated in public datasets. The clinical significance of KLF5 amplification and gene expression in gastric cancer were evaluated. The function of KLF5 in cell proliferation was studied in gastric cancer cell...

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Identifiers

PMID: 33923166
DOI: 10.3390/cells10051002
PMCID: PMC8152363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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