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Genomic profiling informs therapies and prognosis for patients with hepatocellular carcinoma in clinical practice.

BMC cancer - 3 Jun 2024

Song Mengqi, Cheng Haoyue, Zou Hao, Ma Kai, Lu Lianfang, Wei Qian, Xu Zejiang, Tang Zirui, Zhang Yuanzheng, Wang Yinan, Sun Chuandong

Abstract excerpt

Hepatocellular carcinoma (HCC) genomic research has discovered actionable genetic changes that might guide treatment decisions and clinical trials. Nonetheless, due to a lack of large-scale multicenter clinical validation, these putative targets have not been converted into patient survival advantages. So, it's crucial to ascertain whether genetic analysis is clinically feasible, useful, and whether it can be...

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Identifiers

PMID: 38825709
DOI: 10.1186/s12885-024-12407-2
PMCID: PMC11145829

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