Article
Decision forest analysis of 61 single nucleotide polymorphisms in a case-control study of esophageal cancer; a novel method.
BMC bioinformatics - 15 Jul 2005
Xie Qian, Ratnasinghe Luke D, Hong Huixiao, Perkins Roger, Tang Ze-Zhong, Hu Nan, Taylor Philip R, Tong Weida
Abstract excerpt
BACKGROUND: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provide breakthroughs in the understanding of complex diseases. Understanding how the millions of SNPs in the human genome are involved in conferring susceptibility or resistance to disease, or in rendering a drug efficacious or toxic in the...
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