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Article

Spatial and temporal stability of paneth cell phenotypes in Crohn's disease: implications for prognostic cellular biomarker development.

Inflammatory bowel diseases - 1 Apr 2014

Liu Ta-Chiang, Gao Feng, McGovern Dermot P B, Stappenbeck Thaddeus S

Abstract excerpt

BACKGROUND: We previously demonstrated that morphologic defects of ileal Paneth cells correlate with multiple susceptible genetic variants, the presence of granuloma, and clinical outcome in Crohn's disease. These studies were performed using uninvolved areas of resection specimens. To develop Paneth cell phenotype as a prognostic biomarker in Crohn's disease, further characterization is necessary. Specifically,...

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Identifiers

PMID: 24552829
DOI: 10.1097/01.MIB.0000442838.21040.d7
PMCID: PMC4180521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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