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Article

Spatial and temporal stability of paneth cell phenotypes in Crohn's disease: implications for prognostic cellular biomarker development.

Inflammatory bowel diseases - 1 Apr 2014

Liu Ta-Chiang, Gao Feng, McGovern Dermot P B, Stappenbeck Thaddeus S

Abstract excerpt

BACKGROUND: We previously demonstrated that morphologic defects of ileal Paneth cells correlate with multiple susceptible genetic variants, the presence of granuloma, and clinical outcome in Crohn's disease. These studies were performed using uninvolved areas of resection specimens. To develop Pa...

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Identifiers

PMID: 24552829
DOI: 10.1097/01.MIB.0000442838.21040.d7
PMCID: PMC4180521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24552829-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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