Article
Chronic renal insufficiency among Asian Indians with type 2 diabetes: I. Role of RAAS gene polymorphisms.
BMC medical genetics - 3 May 2006
Prasad Pushplata, Tiwari Arun K, Kumar K M Prasanna, Ammini A C, Gupta Arvind, Gupta Rajeev, Sharma A K, Rao A R, Nagendra R, Chandra T Satish, Tiwari S C, Rastogi Priyanka, Gupta B Lal, Thelma B K
Abstract excerpt
BACKGROUND: Renal failure in diabetes is mediated by multiple pathways. Experimental and clinical evidences suggest that renin-angiotensin-aldosterone system (RAAS) has a crucial role in diabetic kidney disease. A relationship between the RAAS genotypes and chronic renal insufficiency (CRI) among type 2 diabetes subjects has therefore been speculated. We investigated the contribution of selected RAAS gene...
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