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Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients.

Nephrology (Carlton, Vic.) - 1 Dec 2008

Ko Gang Jee, Kang Young Sun, Lee Mi Hwa, Song Hye Kyoung, Kim Hyoung Kyu, Cha Dae Ryong

Abstract excerpt

AIM: Inhibition of aldosterone system is beneficial in diabetic nephropathy, and aldosterone synthesis is regulated at the gene-encoding aldosterone synthase (CYP11B2). Considering the role of aldosterone in diabetic nephropathy, genetic polymorphism of this gene may contribute to the development and progression of diabetic nephropathy. In this study, we investigated whether it is associated with diabetic...

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Identifiers

PMID: 18771471
DOI: 10.1111/j.1440-1797.2008.01005.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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