Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-10 promoter microsatellite polymorphisms in systemic lupus erythematosus: association with the anti-Sm immune response.

Rheumatology (Oxford, England) - 1 Nov 2004

Schotte H, Gaubitz M, Willeke P, Tidow N, Assmann G, Domschke W, Schlüter B

Abstract excerpt

OBJECTIVES: Overproduction of interleukin-10 (IL-10) is a pivotal feature in the pathophysiology of systemic lupus erythematosus (SLE). In vitro IL-10 secretion has previously been related to haplotypes of the IL-10 promoter microsatellite polymorphisms IL10.R and IL10.G. Published data concerning the association of IL10.G alleles with susceptibility to SLE are inconsistent in different ethnic populations. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoantigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Interleukin-10

Share to Linkage Disequilibrium

Share to Lupus Erythematosus, Systemic

Share to Ribonucleoproteins, Small Nuclear

Share to snRNP Core Proteins

Source

Identifiers

PMID: 15304673
DOI: 10.1093/rheumatology/keh353

Genes

ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-10 promoter microsatellite polymorphisms in systemic lupus erythematosus: association with the anti-Sm immune response.PMID 15304673Read ↗

Association of extended interleukin-10 promoter haplotypes with disease susceptibility and manifestations in German patients with systemic lupus erythematosus.Semantic proximity Read ↗

Genetic variation in the interleukin-10 gene promoter in Polish patients with systemic lupus erythematosus.Semantic proximity Read ↗

Association of interleukin-10 promoter haplotypes with disease susceptibility and IL-10 levels in Mexican patients with systemic lupus erythematosus.Semantic proximity Read ↗

Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus.Semantic proximity Read ↗

Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus.Semantic proximity Read ↗

Interleukin-10 promoter polymorphisms in patients with systemic lupus erythematosus from the Canary Islands.Semantic proximity Read ↗

Association tests with systemic lupus erythematosus (SLE) of IL10 markers indicate a direct involvement of a CA repeat in the 5' regulatory region.Semantic proximity Read ↗

The role of interleukin-10 promoter polymorphisms in primary Sjogren's syndrome.Semantic proximity Read ↗

Interleukin 10 promoter microsatellite polymorphisms are associated with response to long term treatment with etanercept in patients with rheumatoid arthritis.Semantic proximity Read ↗

Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus.Semantic proximity Read ↗

Association of interleukin-10 promoter polymorphisms with systemic lupus erythematosus.Semantic proximity Read ↗

IL10 promoter polymorphisms are associated with systemic onset juvenile idiopathic arthritis (SoJIA).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.