Article
Integration of transcription and flux data reveals molecular paths associated with differences in oxygen-dependent phenotypes of Saccharomyces cerevisiae.
BMC systems biology - 14 Feb 2014
Lindfors Erno, Jouhten Paula, Oja Merja, Rintala Eija, Orešič Matej, Penttilä Merja
Abstract excerpt
BACKGROUND: Saccharomyces cerevisiae is able to adapt to a wide range of external oxygen conditions. Previously, oxygen-dependent phenotypes have been studied individually at the transcriptional, metabolite, and flux level. However, the regulation of cell phenotype occurs across the different levels of cell function. Integrative analysis of data from multiple levels of cell function in the context of a network of...
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