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Article

A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress.

BMC systems biology - 13 Apr 2011

Achcar Fiona, Camadro Jean-Michel, Mestivier Denis

Abstract excerpt

BACKGROUND: In aerobically grown cells, iron homeostasis and oxidative stress are tightly linked processes implicated in a growing number of diseases. The deregulation of iron homeostasis due to gene defects or environmental stresses leads to a wide range of diseases with consequences for cellular metabolism that remain poorly understood. The modelling of iron homeostasis in relation to the main features of...

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Identifiers

PMID: 21489274
DOI: 10.1186/1752-0509-5-51
PMCID: PMC3094212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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