Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mammalian cells use the autophagy process to restrict avian influenza virus replication

1 Jun 2021

Abstract excerpt

Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. We observe that when IAV containing avian PB2 infects mammalian cells, viral ribonucleoprotein (vRNP) aggregates that localize to the microtubule-organizing center (MTOC) are formed. These vRNP aggregates resemble LC3B-associated autophagosome structures, with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza Virus Research Studies
Share to interferon and immune responses
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34107256
DOI: 10.1016/j.celrep.2021.109213

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mammalian cells use the autophagy process to restrict avian influenza virus replicationPMID 34107256Read ↗

Autophagy Promotes Replication of Influenza A Virus In VitroSemantic proximity Read ↗

Interplay between the cellular autophagy machinery and positive-stranded RNA virusesSemantic proximity Read ↗

Autophagy in Negative-Strand RNA Virus InfectionSemantic proximity Read ↗

Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses.Semantic proximity Read ↗

The battle for autophagy between host and influenza A virusSemantic proximity Read ↗

The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagySemantic proximity Read ↗

Autophagy and RNA virus interactomes reveal IRGM as a common targetSemantic proximity Read ↗

Japanese Encephalitis Virus Activates Autophagy as a Viral Immune Evasion StrategySemantic proximity Read ↗

A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability.Semantic proximity Read ↗

Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagySemantic proximity Read ↗

Virus-Induced Cytoplasmic Aggregates and Inclusions Are Critical Cellular Regulatory and Antiviral FactorsSemantic proximity Read ↗

The Regulation of Autophagy by Influenza A VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.