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Article

Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes

4 Nov 2020

Abstract excerpt

Coxsackievirus B3 (CVB3) is a single-stranded positive RNA virus that usurps cellular machinery, including the evolutionarily anti-viral autophagy pathway, for productive infections. Despite the emergence of double-membraned autophagosome-like vesicles during CVB3 infection, very little is known about the mechanism of autophagy initiation. In this study, we investigated the role of established autophagy factors...

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PMID: 33149253
DOI: 10.1038/s41598-020-76227-7

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